Our MissionWe are using cell fusion as a tool to understand tumor progression, and we are identifying cancers in which illicit fusion as a process contributes to tumorigenesis. We are performing exosome biology to understand tumor-host communication and to devise sensitive and noninvasive diagnostic tools. | |
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TM© and © 1941-2099 Marvel Characters, Inc. All Rights Reserved. | |
Research InterestsOur laboratory's mission is to contribute to reducing cancer incidence. We do so with two foci in basic molecular pathology. One is to develop methods for early detection of abnormal cells using sensitive and noninvasive methods. The other focus is to understand the process of malignant conversion of tumors. | ||
Early Detection |
Malignant Conversion |
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Micrograph of exosomes released from human primary cells. Exosomes are nano-vesicles of defined protein and RNA composition. They are released from most human cells in culture, and they can be found in our blood, saliva, urine, and milk. Micrograph by Steven Hearn (CSHL) and Dominik Duelli. |
2 murine embryonic fibroblasts fusing, and probed with SKY-probes. Picture by Dr. Hesed Padilla-Nash and Dr. Thomas Ried (NIH/NCI) |
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